CD11b-Biotin, human, mouse 30 tests
货号：
130-109-362 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-109-362 |
| 描述 | Clone REA592 recognizes the human and mouse CD11b antigen (Mac-1 α; integrin αM chain), which is part of the CD11b/CD18 heterodimer (Mac-1 α, Mβ2 integrin), also known as the C3 complement receptor. It functions as a receptor for complement (C3bi), fibrinogen, or clotting factor X. In humans, CD11b is strongly expressed on myeloid cells and weakly expressed on NK cells and some activated lymphocytes as well as on microglia in the brain. In mice, the CD11b antigen is expressed on monocytes/macrophages and microglia. To a lower extent it is expressed on granulocytes, NK cells, CD5+ B-1 cells, and subsets of dendritic cells. Clone REA592 recognizes also the non-human primate CD11b antigen. Additional information: Clone REA592 displays negligible binding to Fc receptors. |
| 别名 | integrin αM, Mac-1 α, Integrin alpha-M, CR3A |
| 克隆号 | REA592 |
| 同种亚型 | recombinant human IgG1 |
