CD49f-Biotin, human, mouse 30 tests
货号：
130-107-830 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-107-830 |
| 描述 | Clone REA518 recognizes the human and mouse CD49f antigen, a 120 kD single-pass type I membrane protein, which is also known as integrin alpha-6 (ITGA6). Integrins are integral cell-surface proteins composed of an α chain and a β chain and are involved in cell adhesion as well as cell-surface mediated signaling. CD49f associates with integrin β1 chain (CD29) to form VLA-6 and with integrin β4 chain (CD104) to form the α6 β4 complex, which plays a critical structural role in the hemidesmosome and constitutes a receptor for laminin in epithelial cells. CD49f is furthermore expressed on T cells, monocytes, platelets, endothelial cells, trophoblasts of placenta, and spermatogonial stem cells. Additional information: Clone REA518 displays negligible binding to Fc receptors. |
| 别名 | ITGA6, CD49fB, VLA-6, ITGA6, VLA-6α |
| 克隆号 | REA518 |
| 同种亚型 | recombinant human IgG1 |
