Anti-Hsp70-FITC, human & mouse 30 tests
货号：
130-105-600 基本售价：
询价 规格：
30 tests
产品信息
概述| 货号 | 130-105-600 |
| 描述 | Clone REA349 recognizes the human and mouse heat shock 70 kDa protein (Hsp70) antigen, a member of the Hsp family of heat shock proteins that serve critical roles in protein homeostasis. The HSP70 family is the most conserved in evolution, and all eukaryotes contain multiple members. Their synthesis is increased upon environmental stress. Hsp70 assists a wide range of folding processes, including the folding and assembly of newly synthesized proteins, refolding of misfolded and aggregated proteins, membrane translocation of organellar and secretory proteins, and control of the activity of regulatory proteins. It has thus housekeeping functions in the cell in which it is built-in components of folding and signal transduction pathways, and quality control functions in which it proofreads the structure of proteins and repairs misfolded conformers. All of these activities appear to be based on the property of Hsp70 to interact with hydrophobic peptide segments of proteins in an ATP-controlled fashion. Additional information: Clone REA349 displays negligible binding to Fc receptors. |
| 别名 | HSPA1B, HSPA1A, HSP70-1, HSP70-2, HSP70.1, HSP70.2 |
| 克隆号 | REA349 |
| 同种亚型 | recombinant human IgG1 |
