CD11c-FITC, mouse 100 tests
货号：
130-110-837 基本售价：
询价 规格：
100 tests
产品信息
概述| 货号 | 130-110-837 |
| 描述 | Clone REA754 recognizes the mouse CD11c antigen, also known as integrin αX or Itgax. CD11c is present in dendritic cells in lymphoid organs and blood, in Langerhans cells in the epidermis, in dendritic cell progenitors in the bone marrow, and in in vitro–generated bone marrow–derived dendritic cells. In spleen and lymph node, CD11c is found at high levels on conventional CD11c+CD45R–mPDCA-1– dendritic cells, and at moderate levels on CD11c+CD45R+mPDCA-1+ plasmacytoid dendritic cells. CD11c is reported to be weakly expressed on NK cells, B cells, and T cell subsets. About 1–3% of splenocytes, 2% of bone marrow cells, as well as <1% of lymph node cells and thymocytes express CD11c. CD11c is a receptor for fibrinogen. It mediates cell-cell interaction during inflammatory responses and is involved in monocyte adhesion and chemotaxis.Additional information: Clone REA754 displays negligible binding to Fc receptors. |
| 别名 | p150, integrin αX, ITGAX, CR4 |
| 克隆号 | REA754 |
| 同种亚型 | recombinant human IgG1 |
