Anti-TCR Vb9-FITC, mouse 100 tests
货号:
130-111-056 基本售价:
询价 规格:
100 tests
产品信息
概述货号 | 130-111-056 |
描述 | Clone REA727 recognizes the mouse V beta 9 T cell receptor (TCR Vβ9). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCR Vβ9 is a variant of the TCR β chain and is expressed on mouse strains with the b haplotype (e.g. C57BL/6) in the Tcrb gene complex. The Tcrb-V9 gene locus is deleted in mice having the a (e.g. Balb/c) or c (e.g. SJL, NOD) haplotype. Murine Vβ9+ cells recognize the Mtv-43, Mtv-44, and exogenous MMTV (SW) Mls-1 superantigens.Additional information: Clone REA727 displays negligible binding to Fc receptors. |
别名 | TCR Vb9 |
克隆号 | REA727 |
同种亚型 | recombinant human IgG1 |