CD49d-FITC, mouse 200 tests
货号：
130-102-475 基本售价：
询价 规格：
200 tests
产品信息
概述| 货号 | 130-102-475 |
| 描述 | The monoclonal antibody R1-2 reacts with mouse CD49d, a 150 kDa Integrin family member, also known as integrin α4 chain. Integrins are cell-surface receptors, expressed as heterodimers essential in various processes mediating intercellular or cell-matrix interaction. CD49d associates non-covalently with the integrin ß or ß1 (CD29) forming the complex VLA4, which is expressed on peripheral lymphocytes, thymocytes, eosinophils, basophils, mast cells, dendritic cells, and monocytes. VLA4 plays a critical role in adhesion and migration of cells into tissues by binding to its ligand VCAM-1 (CD106). Together with the ß7 integrin, CD49d forms the heterodimer LPAM-1, which is a ligand for the mucosal vascular addressin (MAdCAM-1). |
| 别名 | ITGA4, Itga4B, VLA-4α |
| 克隆号 | R1-2 |
| 同种亚型 | rat IgG2bκ |
