CD268-FITC, mouse 200 tests
货号：
130-102-476 基本售价：
询价 规格：
200 tests
产品信息
概述| 货号 | 130-102-476 |
| 描述 | Clone 7H22-E16 reacts with CD268, also known as B cell activation factor receptor (BAFF-R), a type III transmembrane TNF receptor family member. CD268 is expressed at high levels on resting B cells, at lower levels on activated B cells, and on a small subset of activated/memory T cells. BAFF, also known as BLys, mediates costimulatory responses in peripheral B and T cells. BAFF is a key regulator for B cell differentiation as well as survival and activation of peripheral B cell populations. Accordingly, CD268 appears to be particularly involved in the regulation of normal B cell survival and maturation, but also in the pathophysiology of aggressive B cell malignancies and autoimmune diseases. |
| 别名 | TNFRSF13c, BR3, BAFFR, Bcmd, Bcmd-1, Lvis22 |
| 克隆号 | 7H22-E16 |
| 同种亚型 | rat IgG1κ |
