CD166-PE, mouse 60 tests
货号：
130-105-489 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-105-489 |
| 描述 | Clone REA370 recognizes the mouse CD166 antigen, a Single-pass type I membrane protein also known as Activated leukocyte cell adhesion molecule (ALCAM). CD166 is a member of the immunoglobulin gene superfamily which is expressed by activated leukocytes and thymic epithelial cells and is a ligand for the lymphocyte antigen CD6. It is also expressed at high levels in the brain and lung, at lower levels in the liver and the kidney, and on a number of cell lines. CD166 expression is pathologically correlated with aggressive disease in a variety of cancers including melanoma, prostate, breast, ovarian, esophageal, and bladder cancers. It is also a universal functional marker of murine and human hematopoietic stem cells (HSC) and osteoblasts within the hematopoietic niche and it is involved in modulating HSC-niche interactions and HSC fate.Additional information: Clone REA370 displays negligible binding to Fc receptors. |
| 别名 | ALCAM, BEN, DM-GRASP, MuSC, SC1 |
| 克隆号 | REA370 |
| 同种亚型 | recombinant human IgG1 |
