CD270 (HVEM)-PE, mouse 60 tests
货号：
130-103-410 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-103-410 |
| 描述 | Clone REA275 recognizes the CD270 antigen, a type I transmembrane protein of the TNF-receptor superfamily which is also known as Herpes virus entry mediator (HVEM) or tumor necrosis factor receptor like 2 (TR2). CD270 is expressed in multiple tissues and cell lines and shows a constitutive and relatively high expression in peripheral blood T cells, B cells, monocytes, neutrophils and dendritic cells. Both human and mouse forms of CD270 can mediate entry of herpes simplex virus-1 and -2 (HSV-1 and HSV-2). CD270 transmits both activating and inhibitory signals; e.g interaction with receptors such as BTLA or CD160 attenuates TCR-mediated signaling, whereas interaction with receptor LIGHT allows co-stimulation of T and B cells.Additional information: Clone REA275 displays negligible binding to Fc receptors. |
| 别名 | TNFRSF14, ATAR, HVEA, HVEM, Tnfrs14 |
| 克隆号 | REA275 |
| 同种亚型 | recombinant human IgG1 |
