CD223-Biotin, mouse, REA776, 100 tests
货号：
130-111-512 基本售价：
询价 规格：
100 tests
产品信息
概述| 货号 | 130-111-512 |
| 描述 | Clone REA776 recognizes an epitope within the D2 domain of murine CD233, also known as LAG-3, which is a 70 kDa high affinity MHC class II ligand. It is expressed on activated CD4+ and CD8+ α/β T cells, on a subset of NK cells, B cells and plasmacytoid dendritic cells. It is proposed, that LAG-3 could be used as a marker of T cell induced B cell activation.In association with the CD3 complex CD223 is a negative regulatory molecule to inhibit TCR-mediated signaling and to regulate homeostatic T cell expansion.Additional information: Clone REA776 displays negligible binding to Fc receptors |
| 别名 | LAG-3, Ly66 |
| 克隆号 | REA776 |
| 同种亚型 | recombinant human IgG1 |
