CD371 (CLEC12A)-Biotin, mouse 200 tests
货号：
130-109-262 基本售价：
询价 规格：
200 tests
产品信息
概述| 货号 | 130-109-262 |
| 描述 | Clone REA594 recognizes the mouse CD371 (CLEC12A) antigen, a 30 kDa type II transmembrane protein with extracellular C-type lectin domains. CD371 (CLEC12A) is a member of the C-type lectin/C-type lectin–like domain (CTL/CTLD) superfamily which have a common protein fold and plays a role in cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, and immune response.CD371 expression is primarily found on granulocytes and monocytes but also on CD8+ dendritic cells (DCs), plasmacytoid DCs, granulocytes, and B cells. It associates with the signaling phosphatases SHP-1 and SHP-2, but not with SHIP and is a negative regulator of granulocyte and monocyte function.Additional information: Clone REA594 displays negligible binding to Fc receptors. |
| 别名 | CLL-1, MICL, DCAL-2 |
| 克隆号 | REA594 |
| 同种亚型 | recombinant human IgG1 |
