CD178-Biotin, mouse 200 tests
货号:
130-101-937 基本售价:
询价 规格:
200 tests
产品信息
概述货号 | 130-101-937 |
描述 | The monoclonal antibody MFL3 recognizes the type II transmembrane glycoprotein mouse CD178, also known as Fas Ligand, FasL or CD95 Ligand, which is a 40 kDa member of the TNF cytokine family expressed on activated lymphocytes such as T cells, NK cells or monocytes as well as in immune-privilaged sites (e.g cornea or testis). CD178 can trigger apoptosis through trimerization of the Fas receptor CD95. Thereby, CD178 and CD95 play a key role in the regulation of the immune system. Cleavage of membrane bound CD178 from the cell surface via matrix metalloproteinases (such as MMP-7) generates soluble CD178 molecules. |
别名 | FasL, APT1LG1, CD95L, TNFSF6, gld |
克隆号 | MFL3 |
同种亚型 | hamster IgG |