Anti-Dectin-1-Biotin, mouse 200 tests
货号：
130-101-845 基本售价：
询价 规格：
200 tests
产品信息
概述| 货号 | 130-101-845 |
| 描述 | Clone REA154 recognizes murine dectin-1, which is approximately 40 kDa type II transmembrane protein, also known as mouse beta-glucan receptor or CLEC7A. It promotes the phagocytosis of intact yeasts and glucan particles such as β-1,3-linked and β-1,6-glucans, thus playing an important role in anti-fungal immunity. Neutrophils and macrophages express relatively higher levels of dectin-1 as compared to dendritic cells and subpopulation of T cells. In cooperation with TLR2 and TLR4, dectin-1 leads to cytokine production in human macrophages and monocytes.Additional information: Clone REA154 displays negligible binding to Fc receptors. |
| 别名 | CLEC7A, BGR, CLECSF12, beta-GR, βGR |
| 克隆号 | REA154 |
| 同种亚型 | recombinant human IgG1 |
