Anti-Aiolos-PE, mouse 60 tests
货号：
130-110-341 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-110-341 |
| 描述 | Clone REA655 recognizes the mouse Aiolos antigen, a member of the Ikaros family of zinc finger transcription factors, also known as IKZF3. The expression is restricted to lymphoid tissues. Aiolos is highly expressed in spleen and mature B cells and at lower levels in thymus and bone marrow. It was first detected in more committed lymphoid progenitors and strongly up-regulated as these differentiate into pre–T and pre–B cell precursors. It is suggested, that the increase of Ikaros and Aiolos in differentiating lymphocytes is essential for normal progression to a mature and immunocompetent state. Aiolos interacts with Ikaros to regulate lymphocyte differentiation.Additional information: Clone REA655 displays negligible binding to Fc receptors. |
| 别名 | IKZF3, Zfpn1a3, Znfn1a3, 5830411O07Rik |
| 克隆号 | REA655 |
| 同种亚型 | recombinant human IgG1 |
