Anti-PIR-A/B-PE, mouse 60 tests
货号：
130-107-022 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-107-022 |
| 描述 | Clone REA472 recognizes both isoforms of the mouse paired immunoglobulin-like receptor (PIR-A and PIR-B) antigen, a single-pass type I membrane protein which is also known as leukocyte immunoglobulin-like receptor 3 (LIR-3). Cell surface expression of PIR molecules on myeloid and B lineage cells increase with cellular differentiation and activation. PIR molecules are also expressed on dendritic cells, monocytes/macrophages, and mast cells in varying levels, but not on T cells and NK cells. PIR-A/B is a receptor for class I MHC antigens and down-regulates antigen-induced B cell–activation by recruiting phosphatases to its immunoreceptor tyrosine-based inhibitor motifs (ITIM). Additional information: Clone REA472 displays negligible binding to Fc receptors. |
| 别名 | 6M21, Ly89, PIRA1, Pir, GP91, LIR-3, LILRB3, PIR-B |
| 克隆号 | REA472 |
| 同种亚型 | recombinant human IgG1 |
