Anti-Dectin-2-Fitc, mouse 60 tests
货号：
130-103-011 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-103-011 |
| 描述 | Clone KVa7-6E7 specifically recognizes mouse dendritic cell–associated C-type lectin 2 (Dectin-2). Dectin-2 is a type II membrane protein and contains a single carbohydrate recognition domain. Like other C-type lectins, mouse Dectin-2 has conserved motifs for the Ca2+-dependent recognition of mannose. Dectin-2 is located in the natural killer gene complex of chromosome 6. Genomic analyses show that beside a full length Dectin-2 transcript two truncated isoforms are produced by alternative splicing, encoding transmembrane proteins of 168–209 amino acids.¹,² The expression of Dectin-2 on mouse monocytes and macrophages can be induced by zymosan and thioglycollate.3 Dectin-2 plays a physiological role in antigen presentation and antigen targeting via Dectin-2 can induce a CD8+ T cell response.4 |
| 别名 | CLEC4N, Clec6a, Clecsf10, Nkcl |
| 克隆号 | KVa7-6E7 |
| 同种亚型 | rat IgG2a |
