Anti-IL-17A-FITC, mouse 60 tests
货号：
130-103-007 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-103-007 |
| 描述 | The Anti-IL-17A antibodies are designed for intracellular staining of IL-17A–producing cells.Interleukin 17 (IL-17) is a family of cytokines that play a central role in adaptive immunity as well as autoinflammatory disorders.1 Data from several mouse models suggest that IL-17 plays a key role in the host defense against certain extracellular bacterial infections.Recently, a new mouse T helper cell subset has been identified, which is dinstinct from Th1 and Th2 cells: IL-17–producing CD4+ T helper (Th17) cells. Th17 cells preferentially produce IL-17A, IL-17F, IL-21, and IL-22. Receptors for IL-17 and IL-22 are expressed on various epithelial tissues, thus Th17 cells are crucial for the cross-talk between immune system and tissues.2 It is now established that Th17 cells are responsible for driving autoimmune inflammation.After stimulation of mouse T cells, IL-17 is not only secreted by CD4+ T cells, but also by CD8+ T cells and γδ T cells. |
| 别名 | CTLA-8, IL-17 |
| 克隆号 | TC11-18H10 |
| 同种亚型 | rat IgG1κ |
