CD94-FITC, mouse 60 tests
货号：
130-104-037 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-104-037 |
| 描述 | Clone 18d3 recognizes CD94, an approximately 70 kDa, single pass, type II transmembrane protein, which belongs to C-type lectin superfamily. CD94 associates covalently with NKG2 family members and forms disulfide bonded heterodimers. CD94-NKG2 receptors bind HLA-E, the nonclassical MHC class Ib molecule. Depending on the associated NKG2 member, CD94-NKG2 heterodimer transmits either activating or inhibitory signal. For e.g via immunoreceptor tyrosine based-inhibitory motifs (ITIMs) containing NKG2A, CD94-NKG2A heterodimers inhibit NK cell cytotoxicity. Besides NK cells, expression of CD94-NKG2 heterodimers is also shown on NK-T cells and a small percentage of CD8+ cells in most mouse strains. DBA/2J mice do not express CD94. |
| 别名 | KLRD1, Kp43 |
| 克隆号 | 18d3 |
| 同种亚型 | rat IgG2aκ |
