CD283 (TLR3)-FITC, mouse 60 tests
货号：
130-103-397 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-103-397 |
| 描述 | Clone 11F8 recognizes CD283 antigen, which is also known as toll-like receptor 3 (TLR3). Toll-like receptors are a family of pattern recognition receptors that have evolved to detect components of foreign pathogens referred to as pathogen associated molecular patterns. TLR3 is a single-pass type I membrane protein expressed exclusively in intracellular vesicles, such as the endoplasmic reticulum (ER), endosomes, lysosomes, and endolysosomes, where it recognizes microbial dsRNA. Multiple cell types are known to express TLR3 including dendritic cells, keratinocytes, and neurons. TLR3 activates antiviral immune responses via the TRIF-dependent pathway and eventually through the production of type I interferon and inflammatory cytokines, suggesting that TLR3 has an essential role in the prevention of viral infection. |
| 别名 | TLR3 |
| 克隆号 | 11F8 |
| 同种亚型 | rat IgG2a |
