Anti-TCR Va3.2 (B,C)-FITC, m 60 tests
货号:
130-106-052 基本售价:
询价 规格:
60 tests
产品信息
概述货号 | 130-106-052 |
描述 | Clone REA395 recognizes the mouse Vα 3.2 T cell receptor (TCR Vα3.2) of mice having the b (e.g., C57BL/6) and c (e.g., SJL, NOD) haplotypes, but not with the strains having the a (Balb/c) or d (DBA/2) haplotype. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. Additional information: Clone REA395 displays negligible binding to Fc receptors. |
别名 | TCRA, TCR Va3.2, TCR-Va3.2 |
克隆号 | REA395 |
同种亚型 | recombinant human IgG1 |