Anti-Ly-6G-FITC, mouse 60 tests
货号：
130-107-974 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-107-974 |
| 描述 | Clone REA526 recognizes the mouse lymphocyte antigen 6G (Ly-6G) antigen, a 21–25 kDa glycosylphosphatidylinositol (GPI) linked protein which is highly expressed on neutrophilic granulocytes. Expression greatly increases during granulocyte maturation. To a lower extent, Ly-6G is also expressed during the development of monocytes. In mouse bone marrow samples, Ly-6G is primarily detected on granulocytes, but not on lymphocytes or erythrocytes. Ligation of Ly-6G in animals with an underlying background inflammation (induced by TNF-α) leads to profound cardiovascular and respiratory responses, including severe breathing difficulties, leukocyte and platelet aggregation, and coagulation, leading to microvessel obstruction and subsequent death.Additional information: Clone REA526 displays negligible binding to Fc receptors. |
| 别名 | Ly-6G.1, Ly-6G.1, Ly6g, Gr-1 |
| 克隆号 | REA526 |
| 同种亚型 | recombinant human IgG1 |
