Anti-F4/80-FITC, mouse 60 tests
货号：
130-102-988 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-988 |
| 描述 | Clone REA126 recognizes F4/80, a member of epidermal growth factor (EGF)-transmembrane 7 (TM7) family. F4/80 is considered as one of the most specific cell-surface markers for murine macrophages. F4/80 is a seven-span transmembrane molecule with a large extracellular, multiple EGF module containing, domain. Constitutive and high expression of F4/80 is found on most resident tissue macrophages, including the spleen, microglia in the brain, Kupffers cells in the liver, and Langerhans cells in the skin. In addition, the expression of F4/80 can also be regulated depending on the physiological status of the cell. F4/80 molecule is required for the differentiation of antigen-specific CD8+ Tregs and is involved in inducing peripheral immune tolerance. No specific ligand for F4/80 has been reported so far. Additional information: Clone REA126 displays negligible binding to Fc receptors. |
| 别名 | ADGRE1, DD7A5-7, EGF-TM7, EMR1, Gpf480, Ly71, TM7LN3 |
| 克隆号 | REA126 |
| 同种亚型 | recombinant human IgG1 |
