CD54 (ICAM-1)-Biotin, mouse 60 tests
货号：
130-104-245 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-104-245 |
| 描述 | Clone REA171 recognizes the murine CD54 antigen, a type I transmembrane glycoprotein also known as intercellular adhesion molecule 1 (ICAM-1). CD54 is continuously present in low concentrations in the membranes of monocytes/macrophages, lymphocytes, activated endothelial cells, granulocytes, and dendritic cells. Its expression is regulated by inflammatory cytokines and can be induced by interleukin-1 and tumor necrosis factor. CD54 is a ligand for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). When activated, leukocytes bind to endothelial cells via CD54/LFA-1 and then transmigrate into tissues.Additional information: Clone REA171 displays negligible binding to Fc receptors. |
| 别名 | ICAM-1, Ly-47, MALA-2 |
| 克隆号 | REA171 |
| 同种亚型 | recombinant human IgG1 |
