CD87-Biotin, mouse
货号：
130-109-896 基本售价：
询价 规格：
EA
产品信息
概述| 货号 | 130-109-896 |
| 描述 | Clone REA630 recognizes the mouse CD87 antigen, a key molecule involved in invasive migration of angiogenic endothelium, also known as uPAR. CD87 binds uPA (urokinase plasminogen activator) and thus facilitates the catalytic C domain of the uPA to come in close proximity of membranebound plasminogen. uPA is a serine protease, which converts plasminogen into plasmin which in turn is involved in digestion of various extracellular matrix proteins. CD87 belongs to the Ly6/neurotoxin receptor family and consists of three disulfide-bonded homologous domains, D1, D2, and D3. Function of uPAR is modulated by two inhibitors, PA1 and PA2. CD87 is expressed in angiogenic endothelial cells.Additional information: Clone REA630 displays negligible binding to Fc receptors. |
| 别名 | U-PAR, uPAR |
| 克隆号 | REA630 |
| 同种亚型 | recombinant human IgG1 |
