Anti-Sca-1-Biotin, mouse 60 tests
货号：
130-101-995 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-101-995 |
| 描述 | Sca-1 (stem cell antigen-1) is a 18 kDa GPI-linked surface protein of the Ly-6 family (Ly-6A/E). The Anti-Sca-1 antibody clone D7 specifically recognizes both Ly-6E.1 and Ly-6A.2, which are gene products of the two Ly-6A/E alleles expressed in different mouse strains (Ly-6E.1: e.g. BALB/c, C3H, NZB; Ly6A.2: e.g. C57BL/6, SJL, 129, AKR).Sca-1 is expressed on hematopoietic stem cells and progenitor cells in mouse bone marrow and one of the defining markers for so-called KSL (c-kit+Sca-1+Lin-) cells. Sca-1 in combination with CD105 (Endoglin) expression has been used to define long-term repopulating hematopoietic stem cells (LTR-HSCs) in mouse bone marrow1,2. In addition, Sca-1+ bone marrow cells also contain the mesenchymal stem cell fraction present. Sca-1+ cells have been shown to give rise to hepatocytes in vivo3 and neural cells in vitro.4 Furthermore, Sca-1 is expressed on stem cells in a variety of nonhematopoietic tissues, such as adult liver5, heart6, and prostate.7 |
| 别名 | LY6A, Ly-6A.2, Ly-6A/E, Ly-6E.1, TAP |
| 克隆号 | D7 |
| 同种亚型 | rat IgG2aκ |
