CD88 (C5AR)-Biotin, mouse 60 tests
货号：
130-106-171 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-106-171 |
| 描述 | Clone 20/70 recognizes the mouse CD88 antigen, a 43 kD G type protein–coupled receptor with seven membrane-spanning regions which is also known as C5a anaphylatoxin chemotactic receptor 1 (C5AR). CD88 is expressed on neutrophils and monocyte/macrophages, but it is also found on hepatocytes, epithelial cells, endothelial cells, tissue mast cells, and human fetal astrocytes. Constitutive CD88 expression was also detected on microglia, and fibroblast-like cells but not by oligodendrocytes. CD88 is a receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. It stimulates chemotaxis, granule enzyme release, and superoxide anion production. Sulfation plays a critical role in the association of CD88 with C5a, but no significant role in the ability of CD88 to transduce a signal and mobilize calcium in response to a small peptide agonist. |
| 别名 | C5AR1, C5AR, C5R1, D7Msu1 |
| 克隆号 | 20/70 |
| 同种亚型 | rat IgG2bκ |
