CD59a-Biotin, mouse 60 tests
货号：
130-104-141 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-104-141 |
| 描述 | Clone REA287 recognizes the CD59a antigen, the murine analog of human CD59 which is also known as MAC-inhibitory protein (MAC-IP) or membrane attack complex inhibition factor (MACIF). CD59a is widely distributed, being present on all circulating cells, epithelia, and endothelia and in most tissues examined. CD59a blocks the formation of the membrane attack complex of complement by inhibiting binding of C9 to the C5b-8 complex, hereby protecting the cells from complement-mediated lysis. Further, CD59a down-modulates CD4+ T cell activity in vitroandin vivo, thereby revealing another link between complement regulators and T cell activation.Additional information: Clone REA287 displays negligible binding to Fc receptors. |
| 别名 | MAC-inhibitory protein (MAC-IP), Membrane attack complex inhibition factor (MACIF), Protectin, CD59 |
| 克隆号 | REA287 |
| 同种亚型 | recombinant human IgG1 |
