CD44-Biotin, mouse 60 tests
货号：
130-102-020 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-020 |
| 描述 | Mouse CD44 is also known as Pgp-1, HCELL, HUTCH-I, HCAM, HERMES, and Ly-24. Clone IM7 reacts with murine CD44, an 80–95 kDa membrane glycoprotein. It is expressed by a variety of hematopoetic and nonhematopoetic cells. Different isoforms are generated by alternative splicing. Clone IM7 reacts with all isoforms and both allelic forms of CD44. CD44 functions as a receptor for hyaluronic acid (HA) and mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 expression is upregulated on naive T cells upon activation and high CD44 expression is maintained on memory T cells. Therefore, CD44 is often used to discriminate CD44hiantigen-experienced T cells from CD44lo(CD62L+) naive T cells. |
| 别名 | HERMES, Ly-24, Pgp-1, CD44s, EMCR III, H-CAM |
| 克隆号 | IM7.8.1 |
| 同种亚型 | rat IgG2bκ |
