CD267 (TACI)-Biotin, mouse 60 tests
货号：
130-102-126 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-126 |
| 描述 | Clone 8F10 recognizes CD267, a type III transmembrane protein receptor that binds to APRIL and BAFF and also interacts with heparan sulfate proteoglycans (HSPGs). Expression of CD267 is found on subset of T cells, marzinal zone (MZ) and, B1 B cells. A dual role of TACI has been suggested in regulating B cell activation. TACI-/- mice have high number of hyper-reactive B cells, indicating an inhibitory role of TACI. On the other hand, mice lacking TACI are unable to mount normal T-cell independent type 2 (TI-2) immune response and thus suggesting a positive role in promoting B cell activation. |
| 别名 | Klrk1, NKG2-D |
| 克隆号 | 8F10 |
| 同种亚型 | rat IgG2aκ |
