CD252-Biotin, mouse 60 tests
货号：
130-102-005 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-005 |
| 描述 | Clone RM134L recognizes CD252 (OX40L), a ligand of OX40 receptor, belonging to the TNF superfamily. Expression of CD252 can be induced on B cells, dendritic cells, macrophages, mast cells, NK cells, endothelial cells and smooth muscle cells. Expression of the cognate receptor OX40, is found on activated CD4 cells, CD8 cells, regulatory T cells, NKT cells, NK cells and neutrophils, but the function of OX40 signalling is extensively studied only in T cells. CD252 (OX40L)-OX40 interaction promotes the proliferation and surival of effector T cells, modulates cytokine production, suppresses the activity of natural regulatory T cells (nTreg) and inhibits the generation of inducible Treg cells. |
| 别名 | TNFSF4, Ath-1, Ath1, CD134L, OX40L, Txgp1, Txgp1l, gp34 |
| 克隆号 | RM134L |
| 同种亚型 | rat IgG2bκ |
