Anti-Sca-1-Biotin, mouse 200 tests
货号：
130-106-426 基本售价：
询价 规格：
200 tests
产品信息
概述| 货号 | 130-106-426 |
| 描述 | Clone REA422 recognizes the mouse Stem Cell Antigen-1 (SCA-1) antigen, a 18 kDa glycosylphosphatidylinositol (GPI) linked protein which is also known as Lymphocyte antigen 6A and 6E (Ly-6A/E). Clone REA422 specifically recognizes both Ly-6E.1 and Ly-6A.2, which are gene products of the two Ly-6A/E alleles expressed in different mouse strains (Ly-6E.1: e.g. BALB/c, C3H, NZB; Ly-6A.2: e.g. C57BL/6, SJL, 129, AKR). Sca-1 is expressed on hematopoietic stem cells and progenitor cells in mouse bone marrow and is one of the defining markers for so-called KSL (c-kit+Sca-1+Lin-) cells. Sca-1 in combination with CD105 (Endoglin) expression has been used to define long-term repopulating hematopoietic stem cells (LTR-HSCs) in mouse bone marrow. In addition, Sca-1+ bone marrow cells also contain the mesenchymal stem cell fraction. Sca-1+ cells have been shown to give rise to hepatocytes in vivo and neural cells in vitro. Furthermore, Sca-1 is expressed on stem cells in a variety of nonhematopoietic tissues, such as adult liver, heart, and prostate.Additional information: Clone REA422 displays negligible binding to Fc receptors. |
| 别名 | LY6A, Ly-6A.2, Ly-6A/E, Ly-6E.1, TAP |
| 克隆号 | REA422 |
| 同种亚型 | recombinant human IgG1 |
