Anti-Qa-1b-Biotin, mouse 60 tests
货号：
130-105-078 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-105-078 |
| 描述 | Clone 6A8.6F10.1A6 recognizes murine Qa-1, a 48kDa non-classical MHC class Ib molecule encoded by the H2-T23 gene on chromosome 17. Qa-1 associates with b2-microglobulin and its surface expression is found on activated hematopoietic cells, T cells, DCs, macrophages and neurons. Murine Qa-1 presents a nine amino acid peptide called Qa-1 determinant modifier (Qdm), peptides from proteins associated with infectious or inflammatory response and a heat shock protein 60 (HSP60)-derived peptide (in the absence of Qdm) to immunoregulatory CD8+ T cells. Qa-1 also serves as a ligand for C-type lectin CD94/NKG2 receptors and depending on the NKG2 family member involved, this interaction can result in an inhibitory or an activating signal. |
| 别名 | H2-T23 |
| 克隆号 | 6A8.6F10.1A6 |
| 同种亚型 | mouse IgG1κ |
