Anti-Plexin-B2-Biotin, mouse 60 tests
货号：
130-106-407 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-106-407 |
| 描述 | Clone REA445 recognizes the mouse Plexin-B2 antigen, a Single-pass type I membrane protein which belongs to the semaphorin receptor family, B subfamily. Plexin-B2 is expressed in the nervous system and on other cells including cells of the immune system. It is expressed on T cells and T-dependent germinal center B cells. Expression is also found on macrophages, conventional dendritic cells and plasmacytoid dendritic cells. Plexin-B2 plays an important role in cell-cell signaling, axon guidance, invasive growth and cell migration. It has several semaphorin ligands including Semaphorin-3E, Semaphorin-4A, Semaphorin-4C, and Semaphorin-4D (CD100). Binding to class 4 semaphorins promotes the downstream activation of RHOA and phosphorylation of ERBB2. During skin damage repairs, CD100 interacts with Plexin-B2 on gamma delta T cells to play a role in the healing process.Additional information: Clone REA445 displays negligible binding to Fc receptors. |
| 别名 | Plxnb2, Debt |
| 克隆号 | REA445 |
| 同种亚型 | recombinant human IgG1 |
