Anti-Ly-49G2-Biotin, mouse 60 tests
货号：
130-102-051 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-051 |
| 描述 | The monoclonal antibody 4D11 recognizes Ly-49G2, which is a inhibitory receptor specific for class Ia MHC molecules. Ly-49G2 belongs to the Ly-49 multigene family, which consists of type II transmembrane homodimeric receptors. Inhibitory Ly-49 members such as Ly-49G2 contain immunoreceptor tyrosine-based inhibitory motif (ITIM) 3 in their cytoplasmic tail and transduce signal that prevents the NK cell cytolytic activity upon recognizing ligands such as H-2Ddk. Expression of Ly-49G2 is found on subsets of natural killer (NK) cells, NK-T cells, and on a population of memory CD8+ T cells (in C57BL/6 mice). |
| 别名 | KLRA7, LGL-1, Ly49G.4, Ly-49G, Ly49g1, Ly-49G2 |
| 克隆号 | 4D11 |
| 同种亚型 | rat IgG2aκ |
