Anti-Ly49d-Biotin, mouse 60 tests
货号：
130-102-119 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-119 |
| 描述 | Clone 4E5 recognizes Ly-49D, a type II transmembrane NK-cell receptor belonging to the Ly-49 family. Members of Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. Ly-49D is a prototypic activating member of Ly-49 family and in contrast to inhibitory members, lacks a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM). A positive signal is initiated by interaction of Ly-49D with immunoreceptor tyrosine-based activating motif (ITAM) containing transmembrane adapter DAP12. Expression of Ly-49D is strain restricted and is found on subsets of NK cells in C57BL/6, C3H/He, and SJL but not in BALB/c, DBA/2, AKR, and CBA/J mice. |
| 别名 | KLRA4, Chok, Klra32, Klra33, Ly-49d |
| 克隆号 | 4E5 |
| 同种亚型 | rat IgG2aκ |
