Anti-GARP (LRRC32)-Biotin, m 60 tests
货号：
130-102-026 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-102-026 |
| 描述 | Clone REA139 recognizes murine GARP, a 80 KDa type I membrane glycoprotein which belongs to the family of leucine rich repeat proteins. Expression of GARP protein is found on megakaryocytes, platelets and activated GARP has been found to be associated with latency associated peptide (LAP), the prodomain responsible for conferring latency to nonactive TGFβ. Thus, GARP as a latent TGFβ binding protein (LTBP) regulates the surface expression of TGFβ and serves as a carrier of LAP, at the cell surface, to immune response active sites, where TGFβ is eventually activated and released to exert further physiological functions such as differentiation of regulatory T cells. Additional Information: Clone REA139 displays negligible binding to Fc receptors. |
| 别名 | LRRC32, Garpin, Glycoprotein A Repetitions Predominant |
| 克隆号 | REA139 |
| 同种亚型 | recombinant human IgG1 |
