Anti-TCR Va11.1, 11.2-Biotin, m 60 tests
货号：
130-107-000 基本售价：
询价 规格：
60 tests
产品信息
概述| 货号 | 130-107-000 |
| 描述 | Clone REA464 recognizes the mouse V alpha 11.1 and 11.2 T cell receptor (TCR Vα11.1, 11.2) of mice having the b (e.g., C57BL/6) and d (e.g., DBA/1, DBA/2, NZW) haplotypes, but not with the strains having the a (Balb/c) or c (e.g., SJL, NOD) haplotype. The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. TCR Vα elements are expressed preferentially in CD4 or CD8 subsets in a manner that is largely independent of the MHC haplotype. It is likely that the Vα elements interact preferentially with conserved regions of class I or class II molecules. Additional information: Clone REA464 displays negligible binding to Fc receptors. |
| 别名 | TCRA, AV11S2, Va11.2, Va11.2b, AV11S1, Va11.1, Va11.1b, TCR-Va11.1, 11.2 |
| 克隆号 | REA464 |
| 同种亚型 | recombinant human IgG1 |
