Ms CD289 (TLR9) PE J15A7 100ug
货号：
565640 基本售价：
14260.0 元 规格：
100ug
产品信息
概述| 货号 | 565640 |
| 描述 | The J15A7 monoclonal antibody specifically binds to the mouse Toll-like receptor 9 (TLR9), which is also known as CD289. It recognizes the TLR9N fragment of mouse TLR9 and does not crossreact with human TLR9. TLR9 is a type I transmembrane protein that belongs to the TLR family whose members play fundamental roles in pathogen recognition and activation of innate immunity. TLR9 recognizes unmethylated CpG sequences in DNA molecules. It is expressed by numerous cells of the immune system including B lymphocytes, monocytes, natural killer cells, and subsets of dendritic cells (DC). It is primarily expressed intracellularly within the endosomal compartments. TLR9 functions to alert the immune system of viral and bacterial infections by binding to microbial DNA that is rich in CpG motifs. TLR9 signaling leads to the activation of cells that produce proinflammatory cytokines, such as type-I interferon and IL-12. It can also help induce B cell proliferative responses. TLR9 can reportedly be detected on the surfaces of some DC subsets. |
| 别名 | TLR9; Tlr9; Toll-like receptor 9; CD289 |
| 同种亚型 | Mouse IgG1, κ |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse TLR9 Transfected Cell Line |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
