Ms FcgmaRIV (CD16-2) PE 9E9 50ug
货号：
565615 基本售价：
10340.0 元 规格：
50ug
产品信息
概述| 货号 | 565615 |
| 描述 | The 9E9 monoclonal antibody specifically binds to Fc receptor, IgG, low affinity IV (Fc γ RIV), which is also known as CD16-2. Fc γ RIV is encoded by Fcgr4 and belongs to the family of receptors for the Fc region of IgG (Fc γ Rs), which also includes Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16) within the Ig superfamily. FcγRIV is expressed on monocytes, macrophages, dendritic cells, and neutrophils. FcγRIV, w hich serves as a ligand-biding subunit, requires the common Fcγ chain for expression and signaling . This complex serves as a cell activating receptor when bound by IgG2a or IgG2b. Fc γ RIV plays various roles in inflammation including neutrophil trafficking and mast cell degranulation. FcγRIV can also function as a low-affinity IgE receptor and promote IgE-induced inflammation. |
| 别名 | CD16-2; Fcgr4; FcgRIV; Fc gammaRIV; FcgammaRIV; Fcgr3a; Fcrl3 |
| 同种亚型 | Armenian Hamster IgG |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse FcγRIV Recombinant Protein |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
