Ms CD123 Biotin 5B11 500ug
货号：
555070 基本售价：
10075.0 元 规格：
500ug
产品信息
概述| 货号 | 555070 |
| 描述 | The 5B11 monoclonal antibody specifically recognizes mouse CD123, the α chain subunit (IL-3R α ) of the mouse IL-3 receptor. The IL-3R α chain is a 60-70 kD transmembrane glycoprotein that binds IL-3 with low affinity but cannot transduce signals by itself. The mouse IL-3R α chain can complex with either of two homologous β chain subunits ( β c and β IL-3) to form high-affinity heterodimeric IL-3 receptors. The β c chain is the common β chain subunit that can complex with the α subunits of the mouse IL-3R, IL-5R and GM-CSFR to form high-affinity receptors. The β IL-3 subunit can form high affinity IL-3 receptor complexes with only the IL-3R α subunit. The β IL-3 subunit clone is specific for mouse IL-3 and binds with low affinity. The immunogen used to generate the 5B11 hybridoma was CTLL cells transfected with the mouse IL-3R alpha chain. The 5B11 antibody does not block the binding of IL-3 protein to the high affinity IL-3 receptor heterodimer. |
| 别名 | Il3ra; IL-3RA; IL-3R-alpha; IL-3 Receptor alpha; IL-3 Receptor α; SUT-1 |
| 同种亚型 | IgG2a |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse IL-3R transfected CTLL cells |
| 标记 | Biotin |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
