Ms CD1d Pure 3C11 500ug
货号：
559871 基本售价：
9834.0 元 规格：
500ug
产品信息
概述| 货号 | 559871 |
| 描述 | The 3C11 antibody reacts with CD1d, a 48-kDa glycoprotein with structural homology to the major histocompatibility complex (MHC) class I molecules. The structure, expression, and functions of CD1 antigens are complex and have been reviewed. mAb 3C11 detects CD1d at varying levels on most types of bone marrow and peripheral leukocytes and on epithelial, dendritic, and lymphoid cells in the thymus. It appears to recognize CD1d only in association with β2m. CD1d has been reported to be expressed by gastrointestinal tract epithelium and in the cytoplasm of hepatocytes as detected viaimmunohistochemical staining of frozen sections with mAb 3C11, suggesting a possible role for CD1d in mucosal immunity. However, CD1d expression was not detectable, viaflow cytometry, on intestinal epithelial cells in studies using the anti-CD1d mAbs 3C11, 1B1 (Cat. no. 553843, for the purified antibody), and 9C7. The 3C11 mAb is reported to cross-react with human CD1d, and it competes with mAb 1B1 (Cat. no. 553844) in binding to mouse splenocytes. |
| 别名 | CD1.1, Ly-38 |
| 同种亚型 | IgM,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | L cells (derived from C3H/An mouse) expressing full-length mouse Cd1.1 cDNA |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.Store undiluted at 4°C.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.5 mg/ml |
