Ms JAML PE 4E10 50ug
货号：
564218 基本售价：
8750.0 元 规格：
50ug
产品信息
概述| 货号 | 564218 |
| 描述 | The 4E10 monoclonal antibody specifically binds to Junctional Adhesion Molecule-Like (JAML) which is also known as JAML1, AMICA, Amica1, Crea7, mCrea7, and Gm638. JAML is a type I transmembrane glycoprotein whose extracellular region contains two immunoglobulin domains. The 4E10 antibody binds to the membrane-proximal D2 Ig domain of JAML which is expressed on g ranulocytes, monocytes, memory T cells and γδ T cells. JAML serves as an endogenous ligand for epithelial and endothelial Coxsackie and Adenovirus Receptor (CAR). The JAML-CAR interaction supports leucocyte migration and the costimulation of TCR-triggered epithelial γδ T cells. The 4E10 antibody can induce costimulatory signals through JAML leading to increased activation, cytokine production and proliferation by epithelial γδ T cells. |
| 别名 | JAML1; AMICA; Amica1; Crea7; mCrea7; Gm638 |
| 同种亚型 | Armenian Hamster IgG |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Skin γδ T Cell Line |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
