Ms IL-27R Alp PE 2918 50ug
货号：
564337 基本售价：
8695.0 元 规格：
50ug
产品信息
概述| 货号 | 564337 |
| 描述 | The 2918 monoclonal antibody specifically binds to the alpha subunit (IL-27 Receptor alpha/IL-27 R α ) of the mouse Interleukin-27 Receptor complex. IL-27 R α is a type I transmembrane glycoprotein that belongs to the type I cytokine receptor family. It is also known as WSX-1 and T cell cytokine receptor (TCCR). IL-27 R α combines with gp130 (CD130) to form a high-affinity cell surface receptor that transduces intracellular signals through the JAK-STAT pathway upon IL-27 binding. IL-27 is a heterodimeric cytokine that is composed of the Epstein-Barr virus-induced gene 3 (EBI3) and IL-27p28 (IL-30) protein subunits. This multifunctional cytokine is produced by activated macrophages, dendritic cells, and epithelial cells. It mediates a broad array of pro- and anti-inflammatory responses. The IL-27 Receptor is expressed by a variety of cell types including naοve T cells and B cells. It is more highly expressed by NK cells and subsets of activated T cells. |
| 别名 | Il27ra; IL-27-R; IL-27Rα; T cell cytokine receptor; TCCR; WSX-1; CRL1 |
| 同种亚型 | Rat LEW, also known as Lewis IgG2a, κ |
| 反应种属 | Mouse (QC Testing) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse TSRR Transfected Cell Line |
| 标记 | PE |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
