Ms NK-T/NK Cell Ag PE U5A2-13 200ug
货号：
550082 基本售价：
7100.0 元 规格：
200ug
产品信息
概述| 货号 | 550082 |
| 描述 | The U5A2-13 mAb recognizes an antigen expressed on most-NKT cells and 55% of NK cells in the liver of various mouse strains, including both NK1.1+ (e.g., C57BL/6) and NK1.1- (e.g., BALB/c, C3H/He, MRL/lpr) strains. Abundant IL-4 and IFN- γ are produced by U5A2-13 Ag+ TCR αβ + cells upon CD3 cross-linking, but not by U5A2-13 Ag- TCR αβ + cells in both NK1.1+ and NK1.1- strains. In C57BL/6 mice (NK1.1+ strain), 80%of U5A2-13 Ag+ T cells co-express the NK1.1 molecule. When staining hepatic mononuclear cells with U5A2-13 mAb, the fluorescence intensity detected on on CD3- cells is lower than on CD3+ cells in BALB/c and C57BL/6 mice. Immunoprecipitation studies have shown that the U5A2-13 antigen comprises three proteins of 65 kDa, 34 kDa, and 31 kDa. This antibody clone U5A2-13 was originally established for mouse NKT cells, but recent studies showed that it recognized a novel conformational epitope of ICAM-1. |
| 别名 | ICAM-1 |
| 同种亚型 | IgG2a,κ |
| 反应种属 | Mouse (QC Testing) |
| 来源宿主 | Rat |
| 使用方法 | FC |
性能| 供应商 | BD Pharmingen |
| 免疫原 | BALB/c nu/nu mouse lymphoma line tMK-2U |
| 标记 | PE |
| 存放说明 | The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
|
| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
