BV510 Hamster Anti-Mouse CD11c
货号：
744178 基本售价：
7000.0 元 规格：
EA
产品信息
概述| 货号 | 744178 |
| 描述 | The N418 monoclonal antibody specifically binds to CD11c, the Integrin alpha X (Integrin α X, Itgax) chain of the heterodimeric gp150, 95 (CD11c/CD18, αXβ2 ) integrin that forms the complement receptor 4 (CR4). CD11c is a150 kDa type I transmembrane glycoprotein that is expressed on dendritic cells, CD4-CD8+ intestinal intraepithelial lymphocytes (IEL), and some NK cells and T cells. CD11c expression is upregulated on IEL and T cells following activation. Cells of the monocyte/macrophage lineage have been reported to express low levels of CD11c. The CD11c/CD18 integrin can bind to several ligands including iC3b, fibrinogen, and CD54. This integrin reportedly plays important roles in phagocytosis and in mediating cellular interactions during inflammation. |
| 别名 | Itgax; Integrin alpha-X; Integrin αX; ITAX; CR4; Complement Receptor 4 |
| 同种亚型 | Armenian Hamster IgG2 |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse Dendritic Cells |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
