BV786 Hamster Anti-Mouse Vδ 6.3/2 TCR
货号：
744477 基本售价：
7000.0 元 规格：
EA
产品信息
概述| 货号 | 744477 |
| 描述 | The 8F4H7B7 antibody reacts with V δ 6.3/2 T-cell Receptor (TCR)-bearing T lymphocytes. Originally defined as a member of the V δ 6 TCR subfamily, it is now proposed that the C57BL-derived V δ 6.3 is an allelic variant of V δ 6.2, found in A/J, AKR, BALB/c, C3H/He, and FVB mice. mAb 8F4H7B7 crossreacts with V δ 6.4 and possibly V δ 6.6 in DBA/2 mice, and it also detects a subset of γδ TCR-bearing cells in CBA/J and C57L mice. It does not recognize V δ 4, V δ 5, V δ 6.1, or V δ 6.5 TCR. A subpopulation of thymocytes expressing V δ 6.3 or V δ 6.4 TCR (in C57BL/6 or DBA/2 mice, respectively) and low levels of CD90.2 (Thy-1.2) shares functional and phenotypic characteristics with NK-T cells. Similar δ V 6.4 TCRexpressing lymphocytes make up significant proportions of the γδ T-cell populations in the liver and spleen of DBA/2 mice. Furthermore, T lymphocytes bearing V δ 6.3/2 TCR are found in the skin and intestinal epithelium and may represent a unique T-cell subpopulation with a potential for autoimmune reactivity. |
| 别名 | V delta 6.3/2 TCR; TCR Vδ 6.3/2; TCR Vδ6.3/2; TCR Vd6.3/2 |
| 同种亚型 | Armenian Hamster IgG2, κ |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | 1E6.11.D7, a C57BL/6 mouse Vγ1.1Vδ6.3 TCR-bearing IEL/T-cell hybridoma |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV786 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
