BV605 Hamster Anti-Mouse FcγRIV (CD16-2)
货号：
742564 基本售价：
7000.0 元 规格：
EA
产品信息
概述| 货号 | 742564 |
| 描述 | The 9E9 monoclonal antibody specifically binds to Fc receptor, IgG, low affinity IV (Fc γ RIV), which is also known as CD16-2. Fc γ RIV is encoded by Fcgr4 and belongs to the family of receptors for the Fc region of IgG (Fc γ Rs), which also includes Fc γ RI (CD64), Fc γ RII (CD32), and Fc γ RIII (CD16) within the Ig superfamily. FcγRIV is expressed on monocytes, macrophages, dendritic cells, and neutrophils. FcγRIV, w hich serves as a ligand-biding subunit, requires the common Fcγ chain for expression and signaling . This complex serves as a cell activating receptor when bound by IgG2a or IgG2b. Fc γ RIV plays various roles in inflammation including neutrophil trafficking and mast cell degranulation. FcγRIV can also function as a low-affinity IgE receptor and promote IgE-induced inflammation. |
| 别名 | CD16-2; Fcgr4; FcgRIV; Fc gammaRIV; FcgammaRIV; Fcgr3a; Fcrl3 |
| 同种亚型 | Armenian Hamster IgG |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse FcγRIV Recombinant Protein |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV605 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
