BV421 Rat Anti-Mouse CD267 (TACI)
货号：
742840 基本售价：
7000.0 元 规格：
EA
产品信息
概述| 货号 | 742840 |
| 描述 | The 8F10 monoclonal antibody specifically recognizes CD267 which is also known as transmembrane activator and calcium-modulating and cyclophilin ligand interactor(transmembrane activator and CAML interactor or TACI). CD267 is encoded by Tnfrsf13b (tumor necrosis factor receptor superfamily member 13B). CD267 is a type III transmembrane protein receptor that binds to the ligands BAFF (BLyS), and APRIL. BAFF overproduction is associated with lupus erythematosus and Sjφgrens disease, two systemic autoimmune diseases. CD267 is expressed most notably on maturing subsets of splenic B cells such as transition type 2 (T2) and marginal zone (MZ) B cells and also in activated T-cells. In CD267 deficient mice, B cell numbers are increased and mice develop autoimmune disorders suggesting that CD267 plays a role in B cell regulation. |
| 别名 | TACI; Taci;Tnfrsf13b; transmembrane activator and CAML interactor |
| 同种亚型 | Rat WF, also known as Wistar Furth IgG2a |
| 反应种属 | Mouse (Tested in Development) |
性能| 供应商 | BD Pharmingen |
| 免疫原 | Mouse TACI Extracellular Domain Protein |
| 存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV421 under optimal conditions that minimize unconjugated dye and antibody.
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| 存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
| 浓度 | 0.2 mg/ml |
