BV650 Rat Anti-Mouse CD155
货号:
743255 基本售价:
7000.0 元 规格:
EA
产品信息
概述货号 | 743255 |
描述 | The 3F1 monoclonal antibody specifically binds to CD155, which is also known as Poliovirus receptor (Pvr) or Tumor-associated antigen 1 (Taa1). CD155 is a type I transmembrane glycoprotein that belongs to the Ig supergene family. CD155 is an adhesion receptor that binds to different ligands including nectin-3, CD96, CD226, TIGIT, and the extracellular matrix protein vitronectin. It is highly expressed on double positive thymocytes and variably expressed on mature thymocytes and T cells, including regulatory T cells and NKT cells. CD155 is also differentially expressed on subsets of B cells, plasma cells, dendritic cells, and monocytes. CD155 expression is upregulated by activated T cells, B cells, and dendritic cells. CD155 is involved in forming adherens junctions between adjacent epithelial or endothelial cells. CD155 plays roles in regulating cell growth, adhesion, motility, migration, and cell-mediated cytotoxicity. CD155-deficient mice exhibit impaired secondary humoral immune responses to orally administered antigens. |
别名 | Poliovirus receptor; Pvr; Tumor-associated antigen 1; Taa1; Tage4; HVED |
同种亚型 | Rat IgG2a, κ |
反应种属 | Mouse (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | Mouse CD155 Recombinant Protein |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV650 under optimal conditions that minimize unconjugated dye and antibody.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |