BV510 Hamster Anti-Mouse TCR Vβ3
货号:
743413 基本售价:
7000.0 元 规格:
EA
产品信息
概述货号 | 743413 |
描述 | The KJ25 antibody specifically reacts with the V β 3 T-cell Receptor (TCR) of strains having the a (e.g., C57BR, SJL), b (e.g., AKR, CBA/Ca, C57BL, DBA/1), and c (e.g., RIII) haplotypes of the Tcrb gene complex. V β 3 TCR-bearing T lymphocytes are clonally eliminated either completely or partially in mice expressing superantigens encoded by the Mtv-1(Mls-4[a], Mls[c]),Mtv-3(Mls[c]),Mtv-6(Mls-3[a], Mls[c]),Mtv-13(Mls-2[a], Mls[c]),Mtv-27,Mtv-44 , and/or Mtv-MAI endogenous proviruses (e.g., A, BALB/c, CBA/J, C3H/He, DBA/2, NZB, NZW). V β 3 TCR-bearing T cells are activated by the superantigenic Staphylococcal Enterotoxins A and B. Activation or elimination of V β 3 TCR-expressing T cells by these determinants is partially dependent upon presentation by I-E. This hamster mAb to a mouse leukocyte antigen does not cross-react with rat leukocytes. |
别名 | TCR V beta 3; TCR Vβ3 |
同种亚型 | Armenian Hamster IgG2, κ |
反应种属 | Mouse (Tested in Development) |
性能供应商 | BD Pharmingen |
免疫原 | αβ TCR purified from mouse T-cell hybridoma 2B4.6 |
存放说明 | Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.
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存储溶液 | Aqueous buffered solution containing ≤0.09% sodium azide. |
浓度 | 0.2 mg/ml |